作者
Caroline L Trotter, Clément Lingani, Katya Fernandez, Laura V Cooper, André Bita, Carol Tevi-Benissan, Olivier Ronveaux, Marie-Pierre Préziosi, James M Stuart
发表日期
2017/8/1
期刊
The Lancet infectious diseases
卷号
17
期号
8
页码范围
867-872
出版商
Elsevier
简介
Background
In preparation for the introduction of MenAfriVac, a meningococcal group A conjugate vaccine developed for the African meningitis belt, an enhanced meningitis surveillance network was established. We analysed surveillance data on suspected and confirmed cases of meningitis to quantify vaccine impact.
Methods
We compiled and analysed surveillance data for nine countries in the meningitis belt (Benin, Burkina Faso, Chad, Côte d'Ivoire, Ghana, Mali, Niger, Nigeria, and Togo) collected and curated by the WHO Inter-country Support Team between 2005 and 2015. The incidence rate ratios (IRRs) of suspected and confirmed cases in vaccinated and unvaccinated populations were estimated with negative binomial regression models. The relative risk of districts reaching the epidemic threshold of ten per 100 000 per week was estimated according to district vaccination status.
Findings
The incidence of …
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CL Trotter, C Lingani, K Fernandez, LV Cooper, A Bita… - The Lancet infectious diseases, 2017