作者
Vera Bril, John England, Gary M Franklin, Miroslav Backonja, Jeffrey Cohen, David Del Toro, Eva Feldman, Donald J Iverson, Bruce Perkins, James W Russell, Douglas Zochodne
发表日期
2011/4/1
来源
Pm&r
卷号
3
期号
4
页码范围
345-352. e21
出版商
No longer published by Elsevier
简介
Objective
To develop a scientifically sound and clinically relevant evidence-based guideline for the treatment of painful diabetic neuropathy (PDN).
Methods
We performed a systematic review of the literature from 1960 to August 2008 and classified the studies according to the American Academy of Neurology classification of evidence scheme for a therapeutic article, and recommendations were linked to the strength of the evidence. The basic question asked was: “What is the efficacy of a given treatment (pharmacological: anticonvulsants, antidepressants, opioids, others; and non-pharmacological: electrical stimulation, magnetic field treatment, low-intensity laser treatment, Reiki massage, others) to reduce pain and improve physical function and quality of life (QOL) in patients with PDN?”
Results and Recommendations
Pregabalin is established as effective and should be offered for relief of PDN (Level A …
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