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This report was produced under the support expenditure of the Third Health Programme in the frame of a specific con-tract with the European Commission, Directorate General for Health and Food Safety acting under the mandate of the European Commission. The content of this report represents the views of the contractor and is its sole responsibility; it can in no way be taken to reflect the views of the European Commission and/or the Directorate General for Health and Food Safety or any other body of the European Union. The European Commission and/or the Directorate General for Health and Food Safety do not guarantee the accuracy of the data included in this report, nor do they accept responsibility for any use made by third parties thereof.