作者
Brooks V Udelsman, Kathleen E Corey, Charlotta Lindvall, Denise W Gee, Ozanan R Meireles, Matthew M Hutter, David C Chang, Elan R Witkowski
发表日期
2019/6/1
期刊
Surgery for Obesity and Related Diseases
卷号
15
期号
6
页码范围
843-849
出版商
Elsevier
简介
Background
Obesity is a known risk factor for nonalcoholic fatty liver disease (NAFLD). However, among individuals undergoing bariatric surgery, the prevalence and risk factors for NAFLD, as well as distinct phenotypes of steatosis, nonalcoholic steatohepatitis (NASH), and fibrosis remain incompletely understood.
Objectives
To determine the prevalence and risk factors for steatosis, NASH, and fibrosis in individuals undergoing routine bariatric surgery.
Setting
Academic medical center in the United States.
Methods
Liver wedge biopsies were performed at the time of surgery between 2001 and 2017. Pathology reports were reviewed, and individuals were grouped by NAFLD phenotype. Covariates including demographic characteristics, co-morbidities, and preoperative laboratory values were compared between groups using Student’s t test, Pearson’s χ2, and logistic regression.
Results
Liver biopsies were obtained in …
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