作者
Gianfranco Delle Fave, Gabriele Capurso, Massimo Milione, Francesco Panzuto
发表日期
2005/10/1
来源
Best practice & research Clinical gastroenterology
卷号
19
期号
5
页码范围
659-673
出版商
Baillière Tindall
简介
Gastric endocrine tumours (gastric carcinoids) usually grow from enterochromaffin-like (ECL) cells. Three types of tumour may be distinguished on the basis of the background gastric pathology: type I, which develops in atrophic body gastritis (ABG); type II, which is associated with multiple endocrine neoplasia and Zollinger–Ellison syndrome; and the sporadic type III, which is not associated with any background pathology. This classification plays a major role in determining the optimal approach to these diseases. In fact, type I carcinoids can be considered to be benign lesions, with exceptional risk of metastases. Type II, in contrast, may be associated with distant metastases, which are also common in type III carcinoids. The therapeutic approach is based mainly on endoscopic excision and somatostatin analogues in types I and II, or on surgical resection in type III. Both types I and II grow under the stimulus of …
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学术搜索中的文章
G Delle Fave, G Capurso, M Milione, F Panzuto - Best practice & research Clinical gastroenterology, 2005