作者
Elettra Merola, Andrea Sbrozzi-Vanni, Francesco Panzuto, Giancarlo D’Ambra, Emilio Di Giulio, Emanuela Pilozzi, Gabriele Capurso, Edith Lahner, Cesare Bordi, Bruno Annibale, Gianfranco Delle Fave
发表日期
2012/4/1
期刊
Neuroendocrinology
卷号
95
期号
3
页码范围
207-213
出版商
S. Karger AG
简介
Background
Type I gastric carcinoids (TIGCs) are neuroendocrine neoplasms arising from enterochromaffin-like cells in atrophic body gastritis. Data regarding their evolution in prospective series are scarce, thus treatment and follow-up are not codified. Our aim was to evaluate clinical outcome and recurrence in TIGCs managed by endoscopic approach.
Methods
33 patients (24 females; median age 65 years, range 23–81) were included and managed through endoscopic follow-up every 6–12 months, with lesion removal and multiple gastric biopsies. Baseline clinical and histological features were analyzed as risk factors by Cox regression.
Results
At diagnosis, 7 tumors were intramucosal carcinoids and 26 were polyps (median diameter 5 mm, range 2–20), multiple in 17 patients. Associated severe atrophy was present in 21 cases (63.6%), while mild atrophy was found in 6 cases (18.2%). During a 46-month …
引用总数
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