作者
Eric I Benchimol, David R Mack, Geoffrey C Nguyen, Scott B Snapper, Wenbin Li, Nassim Mojaverian, Pauline Quach, Aleixo M Muise
发表日期
2014/10/1
期刊
Gastroenterology
卷号
147
期号
4
页码范围
803-813. e7
出版商
WB Saunders
简介
Background & Aims
The Paris pediatric modification of the Montreal classification defines very early onset inflammatory bowel disease (VEO-IBD) as a form of IBD distinct from that of older children. We compared the incidence and outcomes of VEO-IBD with those of IBD in older children.
Methods
We performed a population-based retrospective cohort study of all children diagnosed with IBD in Ontario, Canada, from 1994 through 2009. Trends in standardized incidence were calculated using Poisson regression. We compared outpatient and emergency department visits, hospitalizations, and surgeries among children diagnosed with IBD when they were younger than age 6, ages 6–9.9, and older than age 10 years. Multivariable models were adjusted for income and stratified by sex.
Results
The incidence of IBD increased from 9.4 per 100,000 children (95% confidence interval [CI], 8.2–10.8/100,000 children) in 1994 …
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