作者
Eric I Benchimol, David R Mack, Astrid Guttmann, Geoffrey C Nguyen, Teresa To, Nassim Mojaverian, Pauline Quach, Douglas G Manuel
发表日期
2015/4/1
期刊
Official journal of the American College of Gastroenterology| ACG
卷号
110
期号
4
页码范围
553-563
出版商
LWW
简介
OBJECTIVES:
The risk of inflammatory bowel disease (IBD) contributed by the environment can be elucidated by assessing the risk in migrants from low prevalence to Western countries. The incidence of IBD in immigrants to Canada and their Canadian-born children was compared with nonimmigrants.
METHODS:
A population-based cohort of IBD patients derived from health administrative data was linked to immigration data to determine the standardized incidence of IBD in immigrants to Ontario, Canada, by region of birth between 1994 and 2010. The hazard contributed by younger age at immigration was determined. Incidence for Ontario-born children of immigrant mothers was compared with the children of nonimmigrants.
RESULTS:
In 2,144,660 immigrants, incidence of IBD was 7.3/100,000 person-years compared with 23.9/100,000 in 12,036,921 nonimmigrants (incidence rate ratio (IRR) 0.34, 95% CI 0.26–0 …
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EI Benchimol, DR Mack, A Guttmann, GC Nguyen, T To… - Official journal of the American College of …, 2015