作者
Emilie Le Rhun, Patrick Devos, Thomas Boulanger, Marion Smits, Dieta Brandsma, Roberta Rudà, Julia Furtner, Johann-Martin Hempel, Tjeerd J Postma, Patrick Roth, Tom J Snijders, Frank Winkler, Sebastian Winklhofer, Antonella Castellano, Elke Hattingen, Jaume Capellades, Thierry Gorlia, Martin Van den Bent, Patrick Y Wen, Martin Bendszus, Michael Weller, European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group (BTG) Central Nervous System (CNS) Metastases Committee and the EORTC BTG Imaging Committee
发表日期
2019/5/6
期刊
Neuro-oncology
卷号
21
期号
5
页码范围
648-658
出版商
Oxford University Press
简介
Background
A scorecard to evaluate magnetic resonance imaging (MRI) findings during the course of leptomeningeal metastases (LM) has been proposed by the Response Assessment in Neuro-Oncology (RANO) group.
Methods
To explore the feasibility of the Leptomeningeal Assessment in Neuro-Oncology (LANO) scorecard, cerebrospinal MRIs of 22 patients with LM from solid tumors were scored by 10 neuro-oncologists and 9 neuroradiologists at baseline and at follow-up after treatment. Raters were blinded for clinical data including treatment. Agreement between raters of single items was evaluated using a Krippendorff alpha coefficient. Agreement between numerical parameters such as scores for changes between baseline and follow-up and total scores was evaluated by determining the intraclass coefficient of correlation.
Results
Most raters …
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E Le Rhun, P Devos, T Boulanger, M Smits… - Neuro-oncology, 2019