作者
Simona Malerova, Alzbeta Hejtmankova, EVA Hamsikova, Martina Salakova, Jana Smahelova, Jan Klozar, Ruth Tachezy
发表日期
2020/3/1
期刊
Anticancer research
卷号
40
期号
3
页码范围
1597-1604
出版商
International Institute of Anticancer Research
简介
Background/Aim
The incidence of oropharyngeal tumours induced by human papillomaviruses (HPV) is ever increasing. Information about oral HPV prevalence and its risk factors are very important for future screening and early diagnosis of the disease. The present study aimed to assess oral HPV prevalence in healthy population and risk factors for HPV infection, since this data is scarce or even missing in Central Europe.
Patients and Methods
HPV prevalence in oral rinse and HPV-specific antibodies in peripheral blood were investigated in two groups of healthy participants. Group I consisted of 294 students who reached sexual maturity after the HPV vaccine had been licensed with mean age 23.2 years, and Group II of 215 unvaccinated participants with the mean age 55.7 years. Additionally, the risk factors were evaluated.
Results
In Group I, 2% of participants were positive for oral HPV DNA. A statistically …
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