作者
Mary Prunicki, Nicholas Cauwenberghs, Jennifer Arthur Ataam, Hesam Movassagh, Juyong Brian Kim, Tatiana Kuznetsova, Joseph C Wu, Holden Maecker, Francois Haddad, Kari Nadeau
发表日期
2020/12
期刊
Environmental Health
卷号
19
页码范围
1-17
出版商
BioMed Central
简介
Abstract
Background
Childhood exposure to air pollution contributes to cardiovascular disease in adulthood. Immune and oxidative stress disturbances might mediate the effects of air pollution on the cardiovascular system, but the underlying mechanisms are poorly understood in adolescents. Therefore, we aimed to identify immune biomarkers linking air pollution exposure and blood pressure levels in adolescents.
Methods
We randomly recruited 100 adolescents (mean age, 16 years) from Fresno, California. Using central-site data, spatial-temporal modeling, and distance weighting exposures to the participant’s home, we estimated average pollutant levels [particulate matter (PM), polyaromatic hydrocarbons (PAH), ozone (O3), carbon monoxide (CO) and nitrogen oxides (NOx)]. We collected blood samples and vital signs on health …
学术搜索中的文章
M Prunicki, N Cauwenberghs, JA Ataam, H Movassagh… - Environmental Health, 2020