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Background and Aim: According to the recorded data on the Health Ministry database, a better understanding of clinical and epidemiological factors associated with ESRD can be helpful for decision making about the treatment and preventive interventions with the aim of public health promotion and development of health programs. This study aimed to evaluate the prevalence of ESRD and dialysis-related factors from 2000 to 2009. Material and methods: In this cross sectional study, data were obtained from specific diseases office of the Ministry of Health and Medical Education of the Islamic Republic of Iran from 2000 to 2009. There was no limitation on patient entry. Finally data were analyzed using SPSS software. Results: This study included 12797 patients (57.07% male and 42.57% female) from 2000 to 2009. The overall incidence of ESRD in men (compared to the gender distribution in the normal …