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Extracting meaningful pattern from data can be challenging. Irrelevant, redundant, noisy and unreliable data, misinterpretation of results and incompatibility of a technique to extract unknown patterns from data may lead analyst to develop an erroneous classifier. This research is encouraged by ‘No Free Lunch’ theorem that can be simplified as no classification technique that works best for every problem. This study tries to make a comparison amongst three main approaches in data mining, i.e. Decision Tree (DT), Artificial Neural Network (ANN), and Rough Set Theory (RST). A comparative analysis of the above techniques has been conducted by using open source's software ROSETTA and WEKA on five different datasets. The sample sizes are categorized in relation to the number of attributes and number of instances available in the dataset. Assessments on the classification model are based on accuracy, amount …