作者
Lorraine L Lipscombe, Hadas D Fischer, Peter C Austin, Longdi Fu, R Liisa Jaakkimainen, Ophira Ginsburg, Paula A Rochon, Steven Narod, Lawrence Paszat
发表日期
2015/4
期刊
Breast cancer research and treatment
卷号
150
页码范围
613-620
出版商
Springer US
简介
Women with diabetes have higher breast cancer incidence and mortality. The purpose of this study was to examine the impact of diabetes on stage at breast cancer diagnosis, as a possible reason for their higher mortality. Using population-based health databases from Ontario, Canada, this retrospective cohort study examined stage at diagnosis (II, III, or IV vs I) among women aged 20–105 years who were newly diagnosed with invasive breast cancer between 2007 and 2012. We compared those with diabetes to those without diabetes. Diabetes was defined based on medical records using a validated algorithm. Among 38,407 women with breast cancer, 6115 (15.9 %) women had diabetes. Breast cancer patients with diabetes were significantly more likely to present with advanced-stage breast cancer than those without diabetes. After adjustment for mammograms and other covariates, diabetes was …
引用总数
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