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Wrist-worn inertial measurement units have emerged as a promising technology to passively capture dietary intake data. State-of-the-art approaches use deep neural networks to process the collected inertial data and detect characteristic hand movements associated with intake gestures. In order to clarify the effects of data preprocessing, sensor modalities, and sensor positions, we collected and labeled inertial data from wrist-worn accelerometers and gyroscopes on both hands of 100 participants in a semi-controlled setting. The method included data preprocessing and data segmentation, followed by a two-stage approach. In Stage 1, we estimated the probability of each inertial data frame being intake or non-intake, benchmarking different deep learning models and architectures. Based on the probabilities estimated in Stage 1, we detected the intake gestures in Stage 2 and calculated the F1 score for each …