作者
Muthupandian Saravanan, Venkatraman Gopinath, Mukesh Kumar Chaurasia, Asad Syed, Fuad Ameen, Natarajan Purushothaman
发表日期
2018/2/1
期刊
Microbial pathogenesis
卷号
115
页码范围
57-63
出版商
Academic Press
简介
Zinc oxide nanoparticles (ZnONPs) exhibit abundant biomedical applications. Anisotropic ZnONPs with a defined shape and size were synthesized using Bacillus megaterium (NCIM 2326) cell free extract as a bio-reductant. The study investigated the multidimensional effect of ZnONPs on Helicobacter pylori strains and assessed its biosafety in normal human mesenchymal stem cells (hMSc). The highly stable ZnONPs were produced using B. megaterium and Zinc nitrate as a precursor. The phase of ZnONPs formation and structural characterization were performed by UV- visible (UV-Vis), Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) and Field Emission Scanning electron microscopy (FESEM) analysis. Furthermore, the ZnONPs exhibited higher biocompatibility against human mesenchymal stem cells (hMSC) and proved to be potentially safe in mammalian cells. Corroborating the current …
学术搜索中的文章
M Saravanan, V Gopinath, MK Chaurasia, A Syed… - Microbial pathogenesis, 2018