作者
Frank Van Breusegem, James F Dat
发表日期
2006/6/1
期刊
Plant physiology
卷号
141
期号
2
页码范围
384-390
出版商
American Society of Plant Biologists
简介
Paradoxically, death is an integral part of life. Cell death is essential for growth and development of eukaryotes, by maintaining tissue and organ homeostasis in concert with cell proliferation, growth, and differentiation. Until recently, the wide variety of cell death types reported in the literature was mostly caged in two semantic categories: apoptosis and necrosis. Discrimination between these two forms was based on the presence or absence of specific biochemical and molecular hallmarks, such as DNA laddering, cytochrome c release, caspase involvement, ATP depletion, cytoplasmic swelling, and loss of membrane integrity (Pennell and Lamb, 1997). However, over the last decade this arbitrary division had clearly become too simplistic and a more accurate description of plant cell death needed to be established (van Doorn and Woltering, 2005). To avoid a Babel confusion of languages, we propose necrosis to …
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