作者
Jingnan Xu, Shurou Li, Liqiang Jiang, Xinxin Gao, Wei Liu, Xingyi Zhu, Wenlong Huang, Haiguang Zhao, Zhengkai Wei, Kai Wang, Zhengtao Yang
发表日期
2021/11/1
期刊
International immunopharmacology
卷号
100
页码范围
108097
出版商
Elsevier
简介
Zearalenone (ZEA) is a secondary metabolite produced by fungi such as Fusarium and Fusarium flavum, which is classified as a mycotoxin. Crops and feed in a humid surrounding are widely polluted by ZEA, which further endangering the healthful aquaculture of poultry and even human health. Up to now, prevention and cure of mycotoxicosis is still a crucial subject of poultry husbandry. Baicalin (BAI) is a flavonoid refined from dried roots of Scutellaria baicalensis possessing the function of hepatoprotective, anti-inflammatory, anti-oxidant, and anti-atherosclerotic efficacies.etc. But whether Baicalin also has a protective effect against ZEA intoxication is unclear. Therefore, the aim of this study was to establish a model of ZEA-induced toxic injury in chicks, and then to investigate the way in which Baicalin plays a protective role in the mechanism of ZEA-induced liver and kidney injury in chicks. The results exhibit that …
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