作者
HE Mulnier, HE Seaman, VS Raleigh, SS Soedamah‐Muthu, HM Colhoun, RA Lawrenson
发表日期
2006/5
期刊
Diabetic Medicine
卷号
23
期号
5
页码范围
516-521
出版商
Blackwell Publishing Ltd
简介
Aims  Under‐reporting of diabetes on death certificates contributes to the unreliable estimates of mortality as a result of diabetes. The influence of obesity on mortality in Type 2 diabetes is not well documented. We aimed to study mortality from diabetes and the influence of obesity on mortality in Type 2 diabetes in a large cohort selected from the General Practice Research Database (GPRD).
Methods  A cohort of 44 230 patients aged 35–89 years in 1992 with Type 2 diabetes was identified. A comparison group matched by year of birth and sex with no record of diabetes at any time was identified (219 797). Hazards ratios (HRs) for all‐cause mortality during the period January 1992 to October 1999 were calculated using the Cox Proportional Hazards Model. The effects of body mass index (BMI), smoking and duration of diabetes on all‐cause mortality amongst people with diabetes was assessed (n = 28 725 …
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