作者
Melissa M Amyx, Paul S Albert, Alaina M Bever, Stefanie N Hinkle, John Owen, William A Grobman, Roger B Newman, Edward K Chien, Robert E Gore‐Langton, Germaine M Buck Louis, Katherine L Grantz
发表日期
2019/9
期刊
Paediatric and perinatal epidemiology
卷号
33
期号
5
页码范围
332-342
简介
Background
Birthweight discordance is well studied, with less known about longitudinal inter‐twin differences in foetal growth.
Objective
To examine inter‐twin per cent differences in EFW (EFW%), head (HC%) and abdominal circumference (AC%), and femur length (FL%) across gestation in dichorionic twin gestations and explore associated characteristics.
Methods
Foetal biometrics were assessed by ultrasound and EFW calculated at ≤6 study visits among women with dichorionic twin pregnancies enrolled in the NICHD Fetal Growth Studies cohort (US, 2012‐2013). Inter‐twin per cent difference was defined: ([Sizelarger twin − Sizesmaller twin]/Sizelarger twin × 100). Linear mixed models evaluated per cent differences in foetal biometrics at 15 weeks and their change per week overall and by maternal/neonatal characteristics in unadjusted and adjusted models.
Results
In 140 pregnancies, inter‐twin per …
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