作者
Valérie Bougault, Lionel Loubaki, Philippe Joubert, Julie Turmel, Christian Couture, Michel Laviolette, Jamila Chakir, Louis-Philippe Boulet
发表日期
2012/2/1
期刊
Journal of allergy and clinical immunology
卷号
129
期号
2
页码范围
351-358. e1
出版商
Mosby
简介
BACKGROUND
Airway disorders are common in regular chlorinated swimming pool attendees, particularly competitive athletes, but the impact of intense swimming training on airway function and structure remains unclear.
OBJECTIVE
This study aimed to evaluate airway inflammation and remodeling in elite swimmers.
METHODS
Twenty-three elite swimmers were tested during off-training season. All had exhaled nitric oxide measurement, methacholine test, eucapnic voluntary hyperpnea challenge, allergy skin prick tests, and bronchoscopy with bronchial biopsies. Clinical data and tissues from 10 age-matched mild-asthmatic and 10 healthy nonallergic subjects were used for comparison.
RESULTS
Swimmers had increased airway mucosa eosinophil and mast cell counts than did controls (P < .05). They had more goblet cell hyperplasia and higher mucin expression than did healthy or asthmatic subjects (P < …
引用总数
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学术搜索中的文章
V Bougault, L Loubaki, P Joubert, J Turmel, C Couture… - Journal of allergy and clinical immunology, 2012