作者
Daniel Vitor Vasconcelos-Santos, Danuza O Machado Azevedo, Wesley R Campos, Fernando Oréfice, Gláucia M Queiroz-Andrade, Éricka V Machado Carellos, Roberta M Castro Romanelli, José Nelio Januário, Luciana Macedo Resende, Olindo Assis Martins-Filho, Ana Carolina de Aguiar Vasconcelos Carneiro, Ricardo W Almeida Vitor, Waleska Teixeira Caiaffa, UFMG Congenital Toxoplasmosis Brazilian Group
发表日期
2009/11/1
期刊
Ophthalmology
卷号
116
期号
11
页码范围
2199-2205. e1
出版商
Elsevier
简介
OBJECTIVE
To report results of early ophthalmologic examinations in a large cohort of newborns with congenital toxoplasmosis (CT) after neonatal screening.
DESIGN
Cross-sectional analysis of a cohort.
PARTICIPANTS
A total of 178 newborns with confirmed CT from 146,307 screened babies (95% of live births) from Minas Gerais state, southeastern Brazil.
METHODS
From November 2006 to May 2007, newborns underwent neonatal screening by immunoglobulin (Ig)M capture of dried blood samples. On all positive or suspected cases, confirmative serology was performed on babies and their mothers. Congenital toxoplasmosis was confirmed in newborns who had IgM and/or IgA and IgG, or IgG associated with suggestive ocular lesions (with IgM and IgG in the mother). Ophthalmologic evaluation consisted of indirect ophthalmoscopy with a lid speculum. Pediatric examination and radiologic studies of the …
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DV Vasconcelos-Santos, DOM Azevedo, WR Campos… - Ophthalmology, 2009