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Multiparametric magnetic resonance imaging (mpMRI) is the standard for local prostate cancer (PCa) staging. Whole‐body MRI (wbMRI) has shown capabilities for metastatic screening. This study assesses the feasibility and value of an all‐in‐one AJCC TNM staging of PCa during a unique MRI session combining mpMRI and wbMRI.

Thirty consecutive patients with “high‐risk” PCa prospectively underwent mpMRI of the prostate and wbMRI, in addition to ^99mTc bone scan (BS), completed with standard X‐rays (±TXR) and contrast enhanced CT for distant staging. For the statistical analysis, a “best valuable comparator” (BVC) combining a panel review of all available baseline and follow‐up imaging, biological, and clinical data was used to adjudicate lymph node and bone metastatic status.

Prostate mpMRI was analyzed using ESUR guidelines. Sensitivity of BS ± TXR …