作者
Sunni L Mumford, Sonya S Dasharathy, Anna Z Pollack, Neil J Perkins, Donald R Mattison, Stephen R Cole, Jean Wactawski-Wende, Enrique F Schisterman
发表日期
2013/7/1
期刊
Human reproduction
卷号
28
期号
7
页码范围
1853-1862
出版商
Oxford University Press
简介
STUDY QUESTION
Do uric acid levels across the menstrual cycle show associations with endogenous estradiol (E2) and reproductive hormone concentrations in regularly menstruating women?
SUMMARY ANSWER
Mean uric acid concentrations were highest during the follicular phase, and were inversely associated with E2 and progesterone, and positively associated with FSH.
WHAT IS KNOWN ALREADY
E2 may decrease serum levels of uric acid in post-menopausal women; however, the interplay between endogenous reproductive hormones and uric acid levels among regularly menstruating women has not been elucidated.
STUDY DESIGN, SIZE, DURATION
The BioCycle study was a prospective cohort study conducted at the University at Buffalo research centre from 2005 to 2007, which followed healthy women for one (n …
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SL Mumford, SS Dasharathy, AZ Pollack, NJ Perkins… - Human reproduction, 2013