作者
Brian W Whitcomb, Enrique F Schisterman, Neil J Perkins, Robert W Platt
发表日期
2009/9
期刊
Paediatric and perinatal epidemiology
卷号
23
期号
5
页码范围
394-402
出版商
Blackwell Publishing Ltd
简介
The ‘birthweight paradox’ describes the phenomenon whereby birthweight‐specific mortality curves cross when stratified on other exposures, most notably cigarette smoking. The paradox has been noted widely in the literature and numerous explanations and corrections have been suggested. Recently, causal diagrams have been used to illustrate the possibility for collider‐stratification bias in models adjusting for birthweight. When two variables share a common effect, stratification on the variable representing that effect induces a statistical relation between otherwise independent factors. This bias has been proposed to explain the birthweight paradox.
Causal diagrams may illustrate sources of bias, but are limited to describing qualitative effects. In this paper, we provide causal diagrams that illustrate the birthweight paradox and use a simulation study to quantify the collider‐stratification bias under a range of …
引用总数
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学术搜索中的文章
BW Whitcomb, EF Schisterman, NJ Perkins, RW Platt - Paediatric and perinatal epidemiology, 2009