作者
Christina Frank, Dirk Werber, Jakob P Cramer, Mona Askar, Mirko Faber, Matthias an der Heiden, Helen Bernard, Angelika Fruth, Rita Prager, Anke Spode, Maria Wadl, Alexander Zoufaly, Sabine Jordan, Markus J Kemper, Per Follin, Luise Müller, Lisa A King, Bettina Rosner, Udo Buchholz, Klaus Stark, Gérard Krause
发表日期
2011/11/10
期刊
New England Journal of Medicine
卷号
365
期号
19
页码范围
1771-1780
出版商
Massachusetts Medical Society
简介
Background
We describe an outbreak of gastroenteritis and the hemolytic–uremic syndrome caused by Shiga-toxin–producing Escherichia coli in Germany in May, June, and July, 2011. The consumption of sprouts was identified as the most likely vehicle of infection.
Methods
We analyzed data from reports in Germany of Shiga-toxin–producing E. coli gastroenteritis and the hemolytic–uremic syndrome and clinical information on patients presenting to Hamburg University Medical Center (HUMC). An outbreak case was defined as a reported case of the hemolytic–uremic syndrome or of gastroenteritis in a patient infected by Shiga-toxin–producing E. coli, serogroup O104 or serogroup unknown, with an onset of disease during the period from May 1 through July 4, 2011, in Germany.
Results
A total of 3816 cases (including 54 deaths) were reported in Germany, 845 of which (22%) involved the hemolytic–uremic …
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C Frank, D Werber, JP Cramer, M Askar, M Faber… - New England Journal of Medicine, 2011