作者
Alexander Zoufaly, M An der Heiden, U Marcus, C Hoffmann, HJ Stellbrink, L Voss, J van Lunzen, O Hamouda, ClinSurv Study Group, K Arastéh, D Hampf, F Bergmann, M Warncke, N Brockmeyer, N Mühlbächer, J Rockstroh, J Wasmuth, S Hass, S Reuter, L Rollmann, S Esser, P Schenk‐Westkamp, A Plettenberg, F Kuhlendahl, A Adam, L Weitner, K Schewe, H Goey, S Fenske, T Buhk, HJ Stellbrink, C Hoffmann, J van Lunzen, A Zoufaly, K Wassmus, M Stoll, S Gerschmann, H Horst, S Trautmann, G Fätkenheuer, D Gillor, J Bogner, B Sonntag, B Salzberger, C Fritzsche
发表日期
2012/3
期刊
HIV medicine
卷号
13
期号
3
页码范围
172-181
简介
Objectives
Antiretroviral therapy reduces mortality and morbidity in HIV‐infected individuals most markedly when initiated early, before advanced immunodeficiency has developed. Late presentation for diagnosis and care remains a significant challenge. To guide public health interventions effectively it is crucial to describe the factors associated with late presentation.
Methods
Case surveillance data for all individuals newly diagnosed with HIV infection in Germany in the years 2001–2010 and data for the years 1999–2010 from the German Clinical Surveillance of HIV Disease (ClinSurv) cohort study, a large multicentre observational study, were analysed. Factors associated with late presentation (CD4 count < 350 cells/μL or clinical AIDS) were assessed using descriptive statistics and multivariable logistic regression methods.
Results
Among 22 925 eligible patients in the national surveillance database, 49.5 …
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A Zoufaly, M An der Heiden, U Marcus, C Hoffmann… - HIV medicine, 2012