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URDANETA-BRACHO, Johan S. et al. Antinuclear antibody staining pattern in patients diagnosed with autoimmune diseases in Manabí, Ecuador. Rev. salud pública [online]. 2022, vol. 24, n. 5, 12. Epub Sep 01, 2022. ISSN 0124-0064. https://doi. org/10.15446/rsap. v24n5. 100875.

Objectives

To detect the staining pattern of antinuclear antibodies (ANA) in patients with a presumptive diagnosis of autoimmune diseases (AID).

Materials and Methods

A study was carried out in 2507 patients referred to a private laboratory, who had ANA detected by the indirect immunofluorescence technique (IFI) taking into consideration ethical criteria.

Results

743 patients (29.6%) were positive. Regarding the characteristics of the populations the female sex and age group 40 to 59 years were the most prevalent with 82.6% and 41.2%, respectively, 44.8% showed titers of 1/80 being the mottled pattern the most found with 47.2% and the fine mottled sub-pattern with 35.7%.

Conclusions

It is important to establish parameters associated with the diagnosis of EAI in various areas where precise data are not known, as well as other fortuitous fin-dings in the presence of ANA positivity, also describing the characteristics of the population, patterns found and titers. The correlation of ANA with other pathologies such as SARS-CoV-2 infection and other agents of clinical importance is relevant.