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METHODS

3-year (2014–2016) analysis of our prospectively maintained traumatic brain injury (TBI) database. We included all TBI patients with intracranial hemorrhage (ICH) on anticoagulants. Patients were stratified into two groups, those on NOACs and on warfarin, and were matched in a 1: 2 ratio using propensity score matching for demographics, injury and vital parameters, type, and size of ICH. Outcome measures were progression of ICH, mortality, skilled nursing facility (SNF) disposition, and hospital and intensive care unit (ICU) length of stay (LOS).

RESULTS

We analyzed 1,459 TBI patients, of which 210 patients were matched (NAOCs, 70; warfarin, 140). Matched groups were similar in age (p= 0.21), mechanism of injury (p= 0.61), Glasgow Coma Scale (GCS) score (p= 0.54), Injury Severity Score (p= 0.62), and type and size of ICH (p= 0.09). Patients on preinjury NOACs had higher rate of progression (p …