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BACKGROUND

Patients with spinal trauma are at high risk for venous thromboembolic events (VTE). Guidelines recommend prophylactic anticoagulation but they are unclear on timing of initiation of thromboprophylaxis. The aim of our study was to assess the impact of early versus late initiation of venous thromboprophylaxis in patients with spinal trauma who underwent operative intervention.

METHODS

We performed a 2-year (2013–2014) review of patients with isolated spine trauma (spine-Abbreviated Injury Scale score,≥ 3 and no other injury in another body region with Abbreviated Injury Scale score,> 2) who underwent operative intervention and received thromboprophylaxis postoperatively. Patients were divided into two groups based on the timing of initiation of thromboprophylaxis: early (< 48 hours) and late (≥ 48 hours), and were matched in a 1: 1 ratio using propensity score matching for demographics …