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The strong link between bone mass and body composition is widely recognized but only few studies were selectively performed on healthy subjects with body mass index within normal limits. We aimed to evaluate the influence of body composition on bone mass in apparently healthy young non-obese men and women (n= 40). To reveal the effect of menopausal transition on the fat mass content, fat mass distribution and fat mass-bone mineral density relationship we compared body composition parameters of young healthy non-obese women to body mass index-matched postmenopausal women (n= 20). Despite normal values of body mass index, large variability of the whole-body fat mass content was noted in our study, with limits ranging between 18.6 and 49.7% in women and 22–40.3% in men. Age appeared not to influence significantly the amount of whole-body fat tissue. Fat mass was not related to bone …