作者
Roberto Minutolo, Rajiv Agarwal, Silvio Borrelli, Paolo Chiodini, Vincenzo Bellizzi, Felice Nappi, Bruno Cianciaruso, Pasquale Zamboli, Giuseppe Conte, Francis B Gabbai, Luca De Nicola
发表日期
2011/6/27
期刊
Archives of internal medicine
卷号
171
期号
12
页码范围
1090-1098
出版商
American Medical Association
简介
Background
Ambulatory blood pressure (BP) measurement allows a better risk stratification in essential hypertension compared with office blood pressure measurement, but its prognostic role in nondialysis chronic kidney disease has been poorly investigated.
Methods
The prognostic role of daytime and nighttime systolic BP (SBP) and diastolic BP (DBP) in comparison with office measurements was evaluated in 436 consecutive patients with chronic kidney disease. Primary end points were time to renal death (end-stage renal disease or death) and time to fatal and nonfatal cardiovascular events. Quintiles of BP were used to classify patients.
Results
The mean (SD) age of the patients was 65.1 (13.6) years, and the glomerular filtration rate was 42.9 (19.7) mL/min/1.73 m2; 41.7% of the participants were women, 36.5% had diabetes, and 30.5% had cardiovascular disease. Office-measured SBP/DBP values were 146 …
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R Minutolo, R Agarwal, S Borrelli, P Chiodini, V Bellizzi… - Archives of internal medicine, 2011