查看文章

The reaction of trans-[RuCl₂(PPh₃)₃] (Ph = C₆H₅) with 2-thio-1,3-pyrimidine (HTPYM) and 6-thiopurines (TPs) produced mainly crystalline solids that consist of cis,cis,trans-[Ru(PPh₃)₂(N,S-TPYM)₂] (1) and cis,cis,trans-[Ru(PPh₃)₂(N⁷,S-TPs)₂]X₂ (X = Cl^-, CF₃SO₃^-). In the case of TPs, other coordination isomers have never been isolated and reported. Instead, the mother liquor obtained after filtration of 1 produced red single crystals of trans,cis,cis-[Ru(PPh₃)₂(N,S-TPYM)₂]·2H₃O⁺·2Cl^- (2·2H₃O⁺·2Cl^-). Selected ruthenium(II)−thiobase complexes were studied for their structural, reactivity, spectroscopic, redox, and cytotoxic properties. Single crystals of 1 contain thiopyrimidinato anions chelated to the metal center via N and S. The Ru−N bonds are significantly elongated for 1 [2.122(2) and 2.167(2) Å] with respect to 2 [2.063(3) Å] because of the trans influence from PPh₃. The coordination pseudo-octahedron for 2 …