作者
MR DeBaun, LC Jordan, AA King, J Schatz, E Vichinsky, CK Fox, RC McKinstry, P Telfer, MA Kraut, L Daraz, FJ Kirkham, MH Murad
发表日期
2020/4/28
来源
Blood advances
卷号
4
期号
8
页码范围
1554-1588
出版商
American Society of Hematology
简介
Background
Central nervous system (CNS) complications are among the most common, devastating sequelae of sickle cell disease (SCD) occurring throughout the lifespan.
Objective
These evidence-based guidelines of the American Society of Hematology are intended to support the SCD community in decisions about prevention, diagnosis, and treatment of the most common neurological morbidities in SCD.
Methods
The Mayo Evidence-Based Practice Research Program supported the guideline development process, including updating or performing systematic evidence reviews. The panel used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, including GRADE evidence-to-decision frameworks, to assess evidence and make recommendations.
Results
The panel placed a higher …
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