查看文章

Background:

Despite recent attention and impressive results with damage control resuscitation, the appropriate ratio of blood products to be transfused has yet to be defined. The purpose of this study was to evaluate whether suggested blood product ratios yield superior survival rates.

Materials:

After IRB approval, a retrospective evaluation was performed on all trauma exsanguination protocol (TEP, n= 118) activations from February 1, 2006 to July 31, 2007. A comparison cohort (pre-TEP, n= 140) was selected from all trauma admissions between August 1, 2004 and January 31, 2006 that (1) underwent immediate surgery by the trauma team and (2) received greater than 10 units of PRBC in the first 24 hours. We then compared those who received FFP: RBC (2: 3) and platelet: RBC (1: 5) ratios with those who did not reach these ratios. Multivariate analysis was performed for independent predictors of mortality …