作者
Satish Nagula, Kamron Pourmand, Harry Aslanian, Juan Carlos Bucobo, Tamas A Gonda, Susana Gonzalez, Adam Goodman, Seth A Gross, Sammy Ho, Christopher J DiMaio, Michelle K Kim, Shireen Pais, John M Poneros, David H Robbins, Felice Schnoll-Sussman, Amrita Sethi, Jonathan M Buscaglia, The New York Endoscopic Research Outcomes
发表日期
2018/8/1
期刊
Clinical Gastroenterology and Hepatology
卷号
16
期号
8
页码范围
1307-1313. e1
出版商
WB Saunders
简介
Background & Aims
Endoscopic ultrasound with fine-needle aspiration (FNA) is the standard of care for tissue sampling of solid lesions adjacent to the gastrointestinal tract. Fine-needle biopsy (FNB) may provide higher diagnostic yield with fewer needle passes. The aim of this study was to assess the difference in diagnostic yield between FNA and FNB.
Methods
This is a multicenter, prospective randomized clinical trial from 6 large tertiary care centers. Patients referred for tissue sampling of solid lesions were randomized to either FNA or FNB of the target lesion. Demographics, size, location, number of needle passes, and final diagnosis were recorded.
Results
After enrollment, 135 patients were randomized to FNA (49.3%), and 139 patients were randomized to FNB (50.7%).The following lesions were sampled: mass (n = 210, 76.6%), lymph nodes (n = 46, 16.8%), and submucosal tumors (n = 18, 6.6%). Final …
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S Nagula, K Pourmand, H Aslanian, JC Bucobo… - Clinical Gastroenterology and Hepatology, 2018