作者
Wen-Hui Huang, Sheng-Long Ding, Xi-Yuan Zhao, Kai Li, Hai-Tao Guo, Ming-Zhu Zhang, Qi Gu
发表日期
2023/6/1
来源
Materials Today Bio
卷号
20
页码范围
100639
出版商
Elsevier
简介
Neural tissue engineering (NTE) has made remarkable strides in recent years and holds great promise for treating several devastating neurological disorders. Selecting optimal scaffolding material is crucial for NET design strategies that enable neural and non-neural cell differentiation and axonal growth. Collagen is extensively employed in NTE applications due to the inherent resistance of the nervous system against regeneration, functionalized with neurotrophic factors, antagonists of neural growth inhibitors, and other neural growth-promoting agents. Recent advancements in integrating collagen with manufacturing strategies, such as scaffolding, electrospinning, and 3D bioprinting, provide localized trophic support, guide cell alignment, and protect neural cells from immune activity. This review categorises and analyses collagen-based processing techniques investigated for neural-specific applications …
引用总数
学术搜索中的文章
WH Huang, SL Ding, XY Zhao, K Li, HT Guo, MZ Zhang… - Materials Today Bio, 2023