作者
Gerald P Bodey, Masoud Mardani, Hend A Hanna, Maha Boktour, Jalal Abbas, Essam Girgawy, Ray Y Hachem, Dimitrios P Kontoyiannis, Issam I Raad
发表日期
2002/4/1
期刊
The American journal of medicine
卷号
112
期号
5
页码范围
380-385
出版商
Elsevier
简介
PURPOSE
Candida glabrata is an increasing cause of candidemia, especially at cancer and bone marrow transplant centers where fluconazole is used for antifungal prophylaxis. This yeast is less susceptible to fluconazole in vitro than is Candida albicans. We compared the characteristics of patients who had C. glabrata and C. albicans candidemia at a large cancer center.
SUBJECTS AND METHODS
We searched the microbiological laboratory reports and identified 116 cases of C. glabrata candidemia between 1993 and 1999. The 116 cases of C. albicans candidemia that occurred most closely in time (before or after each case of C. glabrata candidemia) served as the control group. Data were collected from patients’ medical records.
RESULTS
When compared with patients who had C. albicans infection, patients with C. glabrata candidemia more often had an underlying hematologic malignancy (68 [59%] vs …
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GP Bodey, M Mardani, HA Hanna, M Boktour, J Abbas… - The American journal of medicine, 2002