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Candida kruseiis inherently resistant to fluconazole and is emerging as a frequent cause of fungemia in patients with hematologic malignant neoplasms.

To determine the risk and prognostic factors associated withC kruseifungemia in comparison withCandida albicansfungemia in patients with cancer.

Retrospective study of 57 cases ofC kruseifungemia occurring at the M. D. Anderson Cancer Center, Houston, Tex, from 1989 to 1996. TheC kruseicases were compared with 57 cases ofC albicansfungemia with respect to demographics, underlying cancer, Acute Physiology and Chronic Health Evaluation II score, immunosuppression status, chemotherapy, and the use of central venous catheters, as well as fluconazole prophylaxis.

At our institution,C kruseiaccounted for 5% of fungemias during 1989 through 1992 and for 10% during 1993 through 1996. Patients withC krusei …