作者
STARSurg Collaborative, Thomas M Drake, Lok Ka Cheung, Fortis Gaba, James Glasbey, Nathan Griffiths, Rebecca J Helliwell, Tausif Huq, Rachel Khaw, Jonathan Mayes, Saif Khan, Nasir Rafiq, Evelina Woin, J Edward Fitzgerald, Ewen M Harrison, Dmitri Nepogodiev, TM Drake, Thomas M Drake, James Glasbey, Mike Bath, Aditya Borakati, Joshua Burke, Henry Claireaux, Praveena Deekonda, Buket Gundogan, Holly Joyce, Sivesh Kamarajah, Chetan Khatri, Chia Kong, Kenneth A McLean, Lisa Mcnamee, Midhun Mohan, Evelina Woin, J Edward Fitzgerald, Aneel Bhangu, Ewen M Harrison, Dmitri Nepogodiev, Nishkantha Arulkumaran, Samira Bell, Fiona Duthie, Jeremy Hughes, John Prowle, Toby Richards, K Dynes, P Patel, C Wigley, R Suresh, A Shaw, S Klimach, P Jull, D Evans, R Preece, I Ibrahim, V Manikavasagar, FS Brown, P Deekonda, R Teo, DPY Sim, A Borakati, AE Logan, I Barai, H Amin, S Suresh, R Sethi, W Bolton, O Corbridge, L Horne, M Attalla, R Morley, T Hoskins, R McAllister, S Lee, Y Dennis, G Nixon, E Heywood, H Wilson, L Ng, S Samaraweera, A Mills, C Doherty, E Woin, J Belchos, V Phan, T Chouari, T Gardner, N Goergen, JDB Hayes, CS MacLeod, R McCormack, A McKinley, S McKinstry, W Milligan, L Ooi, NM Rafiq, T Sammut, E Sinclair, M Smith, C Baker, APR Boulton, J Collins, HC Copley, N Fearnhead, H Fox, T Mah, J McKenna, V Naruka, N Nigam, B Nourallah, S Perera, A Qureshi, S Saggar, L Sun, X Wang, DD Yang, P Caroll, C Doyle, S Elangovan, A Falamarzi, K Gascon Pera, E Greenan, D Jain, M Lang‐Orsini, S Lim, L O'Byrne, P Ridgway, S Van der Laan, J Wong, J Arthur, J Barclay, P Bradley, C Edwin, E Finch, E Hayashi, M Hopkins, D Kelly, M Kelly, N McCartan, A Ormrod, A Pakenham, J Hayward, C Hitchen, A Kishore, T Martins, J Philomen, R Rao, C Rickards, N Burns, M Copeland, C Durand, A Dyal
发表日期
2018/10
期刊
Anaesthesia
卷号
73
期号
10
页码范围
1214-1222
简介
The peri‐operative use of angiotensin‐converting enzyme inhibitors or angiotensin‐2 receptor blockers is thought to be associated with an increased risk of postoperative acute kidney injury. To reduce this risk, these agents are commonly withheld during the peri‐operative period. This study aimed to investigate if withholding angiotensin‐converting enzyme inhibitors or angiotensin‐2 receptor blockers peri‐operatively reduces the risk of acute kidney injury following major non‐cardiac surgery. Patients undergoing elective major surgery on the gastrointestinal tract and/or the liver were eligible for inclusion in this prospective study. The primary outcome was the development of acute kidney injury within seven days of operation. Adjusted multi‐level models were used to account for centre‐level effects and propensity score matching was used to reduce the effects of selection bias between treatment groups. A total of …
引用总数
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