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This retrospective claim-based study assessed 1-year medical costs associated with second fracture (s) for patients over 50years old with an initial closed hip, clinical vertebral or non-hip non-vertebral (NHNV) fracture using 2002–2008 MarketScan® Commercial and Medicare Supplemental Databases.

Patients with incident fracture and≥ 12-month pre-period and follow-up period from the incident fracture were extracted. Index date was the first subsequent fracture date for patients with subsequent fracture during the 12-month (cases); index dates for patients without subsequent fractures during the 12-month follow-up (controls) were randomly assigned based on the distribution of index dates of cases. Total costs were examined during the 12-month follow-up period using generalized linear models. A decomposition analysis of the incremental costs attributable to the second fracture was …