作者
Mohammad Jalili, Pouya Entezari, Amin Doosti-Irani, Rasoul Masoomi, Hadi Mirfazaelian
发表日期
2016/8/1
来源
The American Journal of Emergency Medicine
卷号
34
期号
8
页码范围
1535-1541
出版商
WB Saunders
简介
Objective
This meta-analysis of trials was conducted to evaluate the impact of desmopressin on renal colic pain relief in comparison to more typically used medications (opioids and nonsteroidal anti-inflammatory drugs [NSAIDs]).
Methods
PubMed, EMbase, Scopus, CINHAL, and Cochrane Central Register of Controlled Trials were searched for clinical trials. Pain reduction and need for rescue treatment were the outcomes of interest.
Results
Ten studies met our inclusion criteria and were analyzed. Pooling of data showed that, on a scale of 1-10, pain reduction after 30 minutes was significantly higher in NSAID in comparison to desmopressin (3.39 with a 95% confidence interval [CI] of 4.62-2.16; P<.01), but this reduction was not significantly different between NSAID and desmopressin-NSAID combination (− 0.28 with 95% CI of − 0.62 to 0.05; P = .01). Summary of relative risk (RR) for the need for rescue treatment in …
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M Jalili, P Entezari, A Doosti-Irani, R Masoomi… - The American Journal of Emergency Medicine, 2016