作者
Harish Nair, Eric AF Simões, Igor Rudan, Bradford D Gessner, Eduardo Azziz-Baumgartner, Jian Shayne F Zhang, Daniel R Feikin, Grant A Mackenzie, Jennifer C Moiïsi, Anna Roca, Henry C Baggett, Syed MA Zaman, Rosalyn J Singleton, Marilla G Lucero, Aruna Chandran, Angela Gentile, Cheryl Cohen, Anand Krishnan, Zulfiqar A Bhutta, Adriano Arguedas, Alexey Wilfrido Clara, Ana Lucia Andrade, Maurice Ope, Raúl Oscar Ruvinsky, María Hortal, John P McCracken, Shabir A Madhi, Nigel Bruce, Shamim A Qazi, Saul S Morris, Shams El Arifeen, Martin W Weber, J Anthony G Scott, W Abdullah Brooks, Robert F Breiman, Harry Campbell
发表日期
2013/4/20
来源
The Lancet
卷号
381
期号
9875
页码范围
1380-1390
出版商
Elsevier
简介
Background
The annual number of hospital admissions and in-hospital deaths due to severe acute lower respiratory infections (ALRI) in young children worldwide is unknown. We aimed to estimate the incidence of admissions and deaths for such infections in children younger than 5 years in 2010.
Methods
We estimated the incidence of admissions for severe and very severe ALRI in children younger than 5 years, stratified by age and region, with data from a systematic review of studies published between Jan 1, 1990, and March 31, 2012, and from 28 unpublished population-based studies. We applied these incidence estimates to population estimates for 2010, to calculate the global and regional burden in children admitted with severe ALRI in that year. We estimated in-hospital mortality due to severe and very severe ALRI by combining incidence estimates with case fatality ratios from hospital-based studies …
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