作者
Nilesh Parekh, Bala Venkatesh, David Cross, Anne Leditschke, John Atherton, William Miles, Adam Winning, Alan Clague, Claire Rickard
发表日期
2000/10
期刊
Journal of the American College of Cardiology
卷号
36
期号
4
页码范围
1328-1335
出版商
American College of Cardiology Foundation
简介
OBJECTIVES
We studied the incidence of myocardial injury in aneurysmal subarachnoid hemorrhage (SAH) using the more sensitive cardiac troponin I (cTnI) assay, correlated changes in cTnI with creatine kinase, MB fraction (CK-MB), myoglobin, and catecholamine metabolite assays, and examined the predictive value of changes in cTnI for myocardial dysfunction.
BACKGROUND
Myocardial injury in aneurysmal SAH as evidenced by elevated CK-MB fraction has been reported. Little published data exist on the value of cTnI measurements in aneurysmal SAH.
METHODS
Thirty-nine patients were studied for seven days. Clinical cardiovascular assessment, electrocardiographic (ECG), echocardiography, cTnI, CK, CK-MB and CK-MB index, myoglobin and 24-h urinary catecholamine assays were performed in all patients. The ECG abnormalities were defined by the presence of ST-T changes, prolonged QT intervals …
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N Parekh, B Venkatesh, D Cross, A Leditschke… - Journal of the American College of Cardiology, 2000