作者
Gaurav Jain, Pranav Bansal, Bashir Ahmad, Dinesh K Singh, Ghanshyam Yadav
发表日期
2012/1
期刊
Indian journal of palliative care
卷号
18
期号
1
页码范围
45-51
出版商
Wolters Kluwer--Medknow Publications
简介
Background:
This prospective double-blind trial was undertaken to analyze the role of perioperatively administered dexmedetomidine on the occurrence of chronic pain in cases undergoing surgery for breast cancer.
Subjects and Methods:
Eighty-six cases were randomly assigned to two groups to receive either dexmedetomidine (2 μg/ml) in group D or saline in group C, in a loading dose of 0.5 ml/kg, intravenous (IV), 30 min prior to induction, followed by a continuous infusion of 0.25 ml/kg/h IV till the completion of surgery, and then the dose tapered to 0.1 ml/kg/h for up to 24 h. The standardized questionnaires that measured chronic pain (Brief Pain Inventory, BPI; Short Form McGill Pain Questionnaire, SF-MPQ2) and quality of life (Quality of Life Scale, QOLS) were gathered after 3 months of surgery as a primary outcome. Pain (verbal numerical score, VNS), sedation scores (Ramsay scoring), and analgesic …
学术搜索中的文章
G Jain, P Bansal, B Ahmad, DK Singh, G Yadav - Indian Journal of Palliative Care, 2012