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Development of modern biotechnological achievements resulted in the Genetic modification or genetic engineering in the form of genetically modified plants and genetically modified organisms and ultimately the outcomes in the form of genetically modified food, which can be a key point to eradicate hunger, poverty and malnutrition from the country, however some labeling issues, mis and myth conceptions resulted in the failure of all biotechnological advancement. This review indicate the mechanism of group of actions with various biotechnological tool utilize to carry out genetic modification, their benefits, labeling issues etc. India has approved cultivation of some GM crops but due to lack of proper knowledge and religious factors lead to stunted outcomes ignoring environment cleanliness and hunger of malnourished segments. So more attention still needed for its adoption globally by ensure its safety for human utilization.