作者
Stacey J Butler, Alexander V Louie, Rinku Sutradhar, Lawrence Paszat, Dina Brooks, Andrea S Gershon
发表日期
2023/11/11
期刊
Translational Lung Cancer Research
卷号
12
期号
11
页码范围
2260
出版商
AME Publications
简介
Background
Chronic obstructive pulmonary disease (COPD) and lung cancer commonly coexist and have significant symptom overlap. We sought to compare the symptom burden of lung cancer patients with COPD to those without COPD.
Methods
We conducted a retrospective, cross-sectional study of stage I–IV lung cancer patients in Ontario, Canada, who completed the Edmonton Symptom Assessment Scale (ESAS) within 90 days of diagnosis. COPD was ascertained using a validated algorithm and patients were grouped as: no COPD, previously diagnosed COPD (at least 90 days prior to lung cancer diagnosis), and newly diagnosed COPD (within 90 days of lung cancer diagnosis). The association between COPD status and any moderate to severe symptom (ESAS≥ 4) and the number of moderate to severe symptoms was determined using multivariable modified Poisson regression analyses. Multivariable …
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SJ Butler, AV Louie, R Sutradhar, L Paszat, D Brooks… - Translational Lung Cancer Research, 2023