作者
Aditi Sahu, Oriol Yélamos, Nicusor Iftimia, Miguel Cordova, Christi Alessi-Fox, Melissa Gill, Gopi Maguluri, Stephen W Dusza, Cristián Navarrete-Dechent, Salvador González, Anthony M Rossi, Ashfaq A Marghoob, Milind Rajadhyaksha, Chih-Shan J Chen
发表日期
2018/8/22
期刊
JAMA dermatology
简介
Importance
The limited tissue sampling of a biopsy can lead to an incomplete assessment of basal cell carcinoma (BCC) subtypes and depth. Reflectance confocal microscopy (RCM) combined with optical coherence tomography (OCT) imaging may enable real-time, noninvasive, comprehensive three-dimensional sampling in vivo, which may improve the diagnostic accuracy and margin assessment of BCCs.
Objective
To determine the accuracy of a combined RCM-OCT device for BCC detection and deep margin assessment.
Design, Setting, and Participants
This pilot study was carried out on 85 lesions from 55 patients referred for physician consultation or Mohs surgery at Memorial Sloan Kettering Skin Cancer Center in Hauppauge, New York. These patients were prospectively and consecutively enrolled in the study between January 1, 2017, and December 31, 2017. Patients underwent imaging, with the …
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