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Purpose

To evaluate the impact of breast cancer family history and maternal BRCA1/2 mutation on the psychosocial adjustment and perceived risk in girls age 11 to 19 years old.

Materials and Methods

Girls age 11 to 19 years old with one or more relatives with breast cancer or a familial BRCA1/2 mutation (breast cancer family history [BCFH] positive, n= 208; n= 69 with BRCA1/2-positive mother), peers (BCFH negative, n= 112), and their mothers completed assessments of psychosocial adjustment, breast cancer–specific distress, and perceived risk of breast cancer.

Results

General psychosocial adjustment did not differ significantly between BCFH-positive and BCFH-negative girls, either by self-report or mother report, except for higher self-esteem among BCFH-positive girls (P=. 01). BCFH-positive girls had higher breast cancer–specific distress than BCFH-negative girls (P<. 001), but girls from BRCA1/2-positive …