作者
Elsayed GE Elsakka, Ahmed I Abulsoud, Hesham A El-Mahdy, Ahmed Ismail, Mohammed S Elballal, Sherif S Abdel Mageed, Emad Gamil Khidr, Osama A Mohammed, Omnia M Sarhan, Samy Y Elkhawaga, Ahmed A El-Husseiny, Nourhan M Abdelmaksoud, Aya A El-Demerdash, Reem K Shahin, Heba M Midan, Mahmoud A Elrebehy, Ayman A Doghish, Ahmed S Doghish
发表日期
2023/8/1
来源
Pathology-Research and Practice
卷号
248
页码范围
154613
出版商
Urban & Fischer
简介
MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in regulating gene expression. They are significant in many biological and pathological processes and are even detectable in various body fluids such as serum, plasma, and urine. Research has demonstrated that the irregularity of miRNA in multiplying cardiac cells is linked to developmental deformities in the heart's structure. It has also shown that miRNAs are crucial in diagnosing and progressing several cardiovascular diseases (CVDs). The review covers the function of miRNAs in the pathophysiology of CVD. Additionally, the review provides an overview of the potential role of miRNAs as disease-specific diagnostic and prognostic biomarkers for human CVD, as well as their biological implications in CVD.
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